After more than a decade in which only one PrEP option — a daily pill — was available to prevent acquiring HIV, several new PrEP products are entering the scene. But a big test is ahead for these formulations: Will they be introduced in a way that is accessible, acceptable and affordable to those who need them most?
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Last month, we attended HIVR4P 2024 in Lima, Peru. The conference was jam-packed with new and exciting research being presented on HIV prevention, from new methods in the research and development pipeline to results from implementation studies and insights on advances in HIV vaccine research. These are our reflections.
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MOSAIC is heading to Lima, Peru, for the HIV Research for Prevention Conference (HIVR4P 2024). We invite conference attendees to join us for the following sessions.
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For the first time, with the PrEP ring and CAB PrEP entering markets alongside oral PrEP, women have multiple HIV prevention methods to choose from. Now prevention programs face another first: how to deliver those options in ways that ensure informed choice and foster effective use. To help answer that question, MOSAIC embedded a quality improvement collaborative into its flagship CATALYST study.
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Three MTN studies – REACH, DELIVER, and B-PROTECTED – recently published critical new data on PrEP ring use among adolescent girls and young women (AGYW), pregnant individuals, and breastfeeding individuals in Africa. All studies offer compelling evidence that the ring is safe for use among these populations.
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The world is closer than ever to ending HIV as a public health threat. As the global response to the HIV epidemic continues to transition from an emergency response to one focused on sustaining the progress we’ve made, it is critical that we continue to find innovative solutions to address new challenges.
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Expanding access to and uptake of PrEP products among young people, especially adolescent girls and young women, will be key to ending the HIV epidemic. But how do we ensure HIV prevention efforts resonate with and are effective for young millennials and Gen Z? What does meaningful youth engagement in PrEP delivery really mean?
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What sets CATALYST apart is the study’s emphasis on meaningful involvement of young people at every stage of the research to understand end-user perspectives and help tailor the study to meet their needs. This makes us hopeful because the inclusion of young people in the CATALYST journey has not been tokenistic; rather our contributions have been reflected in the whole process so far. In this post, we describe three ways youth have been engaged in CATALYST.
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We are excited to announce the launch of Catalyzing Access to New Prevention Products to Stop HIV (CATALYST), MOSAIC’s flagship product introduction study. CATALYST will provide and assess an enhanced service delivery package that includes oral PrEP, the PrEP ring, and injectable cabotegravir for PrEP.
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As new PrEP products move out of clinical trials and toward market entry, implementation research has a pivotal role to play in guiding the introduction and scale-up of these new products in real-world service delivery settings.
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